For gravide i LAR er det utarbeidet egne nasjonale faglige retningslinjer utgitt av Helsedirektoratet.Fra gammel tid har guy anvendt udtræk fra opiumsvalmuen i smertebehandling og disse midler er baseret på naturlige opioider eller de er kunstigt fremstillet og med en virkning som de naturlige. Denne gruppe af midler anvendes mod stærke smerter.
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